Holly Willoughby issues heartfelt message to fans as she quits Celebrity Juice
and live on Freeview channel 276
The TV presenter, 39, has left her team captain role after 12 years on the ITV2 show.
Her friend Fearne Cotton, 38, quit the long-running series, starring Keith Lemon, 47, in 2018.
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Hide AdWilloughby said she had enjoyed "12 years of fantastic chaos...
"I can't quite believe what we've done and how quick that time has gone," she posted on Instagram.
"Thank you to you all for watching. We've always had the loudest and best audiences....
"It's never felt like work and always been to me like a night out," the co-host of This Morning said.
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Hide Ad"Thank you for all your ingenious ideas and hard work... All good things must come to an end and nothing lasts forever.
"It's time for me to hand over my team captain seat to some lucky, lucky person."
She said of Lemon: "I remember starting this journey with you and saying 'I think this might work'. My goodness me it did.
"Three friends, you me and Fearne Cotton ... and that is what is at the heart of it, friendship. I love the bones of you Lemon!
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Hide Ad"Thank you for making me laugh for 12 years... I'll be back as a guest and just to make sure someone is keeping you in check."
Lemon - real name Leigh Francis - wrote on Twitter: "I've had a lovely time working with you. You are the best! I hope I'm lucky enough to work with you again one day."